Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067956 | 0.94 | ITGB3 (0.35) | ITGB3ITGA2B | |
| SCHEMBL7059050 | 0.87 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL1072330 | 0.85 | KDM4E (0.35) | ITGB3ITGA2BKDM4E | |
| SCHEMBL1072337 | 0.84 | ITGB3 (0.36) | ITGB3ITGA2BKDM4EGLA | |
| SCHEMBL1069863 | 0.83 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL7059871 | 0.82 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL1072536 | 0.81 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL27557111 | 0.79 | ITGB3 (0.34) | ITGB3ITGA2B | |
| SCHEMBL1072341 | 0.79 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL8311626 | 0.78 | ALDH1A1 (0.36) | ITGB3ITGA2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307226-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | Bristol-Myers Squibb Pharma Company (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001097848-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |