Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789532 | 1.00 | MCHR1 (0.54) | MCHR1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL16902862 | 0.90 | MEN1 (0.51) | MCHR1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL10605456 | 0.88 | MCHR1 (0.51) | MCHR1CARM1PRMT1PDE5APDE4A | |
| SCHEMBL5473677 | 0.82 | HRH1 (0.58) | MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL3120094 | 0.82 | MEN1 (0.45) | MCHR1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL2242864 | 0.82 | MCHR1 (0.51) | MCHR1CARM1PRMT1PDE5APDE4A | |
| Hydrochloric Acid SCHEMBL5460821 | 0.81 | HRH1 (0.57) | MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL21047681 | 0.81 | MEN1 (0.47) | MCHR1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL19829484 | 0.80 | HRH1 (0.55) | MCHR1CARM1PRMT1PDE5APDE4A | |
| SCHEMBL11066008 | 0.80 | NOS3 (0.51) | MEN1KMT2AL3MBTL1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877180-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | Biogen Idec MA Inc. (US) | 2015-06-03 | — | — | EP | disclosed |
| WO-2014018891-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-01-30 | — | — | WO | disclosed |
| EP-1027316-B1 | SYNTHESIS OF ARYL ETHERS, METHODS AND REAGENTS RELATED THERETO | MASSACHUSETTS INST TECHNOLOGY (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-1254884-A2 | Preparation of vinyl ethers from alcohols and alkenes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1245553-A2 | Palladium-catalysed synthesis of aryl ethers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-02 | — | — | EP | disclosed |
| US-20010008942-A1 | Synthesis of aryl ethers | BUCHWALD STEPHEN L (US) | 2001-07-19 | — | — | US | disclosed |
| US-6166226-A | Synthesis of aryl ethers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-12-26 | — | — | US | disclosed |
| EP-1027316-A1 | SYNTHESIS OF ARYL ETHERS, METHODS AND REAGENTS RELATED THERETO | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5847166-A | Synthesis of aryl ethers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1998015515-A1 | SYNTHESIS OF ARYL ETHERS, METHODS AND REAGENTS RELATED THERETO | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1998-04-16 | — | — | WO | disclosed |
| US-5516577-A | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5503910-A | HAVING LIGHT EMITTING LAYERS CONTAINING COMPOUNDS WITH SPECIFIED FLUORESCENCE PEAK WAVELENGTHS; EFFICIENCY, STABILITY | IDEMITSU KOSAN CO., LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0459495-B1 | Process for the acylation of naphthylethers with the aid of zeolite-catalysts | HOECHST AG (DE) | 1995-01-25 | — | — | EP | disclosed |
| EP-0569827-A2 | Organic electroluminescence device | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |
| US-5227529-A | Low temperature, catalyst selectivity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| EP-0459495-A2 | Process for the acylation of naphthylethers with the aid of zeolite-catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-04 | — | — | EP | disclosed |
| US-4452943-A | ADDING NITRILE-CONTAINING MATERIAL TO NON-POLAR THERMOPLASTIC POLYMER | GOLDMAN CONRAD | 1984-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008942-A1 | Synthesis of aryl ethers | AHR, PAH, PDK1 | MCHR1 3247/4885MEN1 459/4885KMT2A 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.