SCHEMBL70601

SCHEMBL70601

Oc1ccc(Sc2ccc(O)c(Br)c2)cc1Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.54
BCL2 P10415 4/20 0.43
MCL1 Q07820 4/20 0.43
NR1H2 P55055 1/20 0.42
ALOX12 P18054 2/20 0.39
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
PRMT1 Q99873 1/20 0.35
EP300 Q09472 1/20 0.34
AMY1A P0DUB6 1/20 0.34
MEN1 O00255 2/20 0.33
HPGD P15428 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633861 0.88 MAOA (0.44) ALOX15BCL2MCL1NR1H2ALOX12
SCHEMBL28287220 0.81 ALOX15 (0.50) ALOX15MCL1ALOX12PRMT1EP300
SCHEMBL9199758 0.81 MCL1 (0.52) ALOX15MCL1ALOX12MEN1HPGD
SCHEMBL8634860 0.79 PTGIR (0.39) ALOX15BCL2MCL1KMT2AGAA
SCHEMBL8635450 0.79 ALDH1A1 (0.44) ALOX15MEN1HPGDKMT2AHSD17B10
SCHEMBL3716721 0.76 ALOX15 (0.45) ALOX15BCL2MCL1ALOX12PRMT1
SCHEMBL5634830 0.76 ALOX15 (0.45) ALOX15ALOX12MAOAMAOBPRMT1
SCHEMBL9058669 0.76 APP (0.48) ALOX15BCL2MCL1NR1H2HPGD
SCHEMBL29661904 0.76 MAOA (0.39) BCL2MCL1NR1H2MAOAMAOB
SCHEMBL28441480 0.76 MAOA (0.39) BCL2MCL1NR1H2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542256-B1 Polycarbonate resin solution for forming thermal-sublimating dye receiving layer film MITSUBISHI GAS CHEMICAL CO (JP) 1996-04-24 EP claimed
US-5427998-A Method for preparing a thermal transfer image-receiving sheet involving a polycarbonate dye-receiving layer MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 1995-06-27 US claimed
EP-0542256-A1 Polycarbonate resin solution for forming thermal-sublimating dye receiving layer film MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-05-19 EP claimed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20080318108-A1 Solid Electrolyte, Membrane and Electrode Assembly, and Fuel Cell FUJIFILM CORPORATION 2008-12-25 US disclosed
US-7442459-B2 Solid electrolyte, membrane and electrode assembly, and fuel cell FUJIFILM CORPORATION (JP) 2008-10-28 US disclosed
US-20070264551-A1 Membrane/Electrode Assembly and Fuel Cell FUJIFILM CORPORATION (JP) 2007-11-15 US disclosed
US-5212281-A Catalytic condensation polymerization in solvents of halogenated dihydroxy compounds THE DOW CHEMICAL COMPANY (US) 1993-05-18 US disclosed
US-5194653-A Useful in making heat resistant liquid crystalline polymers NIPPON PAINT COMPANY, LIMITED (JP) 1993-03-16 US disclosed
WO-1993003083-A1 PROCESS FOR THE PREPARATION OF HIGH MOLECULAR WEIGHT HALOGENATED POLYCARBONATE THE DOW CHEMICAL COMPANY (US) 1993-02-18 WO disclosed
WO-1993002123-A1 PROCESS FOR PREPARING HALOGENATED POLYCARBONATE THE DOW CHEMICAL COMPANY (US) 1993-02-04 WO disclosed
EP-0500128-A2 Polycarbonate resin solution for film formation by casting MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-08-26 EP disclosed
EP-0500129-A2 Polycarbonate resin solution for film formation by casting MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-08-26 EP disclosed
US-5081218-A HALOGENATED COPOLYCARBONATES HAVING IMPROVED END GROUP SELECTIVITY AND RESISTANCE TO DEGRADATION THE DOW CHEMICAL COMPANY (US) 1992-01-14 US disclosed
EP-0457334-A1 Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1991-11-21 EP disclosed
EP-0441369-A2 Halogenated copolycarbonates having improved end group selectivity and resistance to degradation THE DOW CHEMICAL COMPANY (US) 1991-08-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALOX15 1966/4885BCL2 3819/4885MCL1 4705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.