SCHEMBL7060139

SCHEMBL7060139

C=CC=CC(C=Cc1ccccc1)=C(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
GLA P06280 1/20 0.44
MAPT P10636 6/20 0.43
MAOB P27338 5/20 0.43
CYP1B1 Q16678 4/20 0.43
PLIN1 O60240 2/20 0.43
LMNA P02545 2/20 0.43
RECQL P46063 2/20 0.43
PLIN5 Q00G26 2/20 0.43
ABHD5 Q8WTS1 2/20 0.43
BCHE P06276 1/20 0.43
TNFRSF1A P19438 1/20 0.43
ACHE P22303 1/20 0.43
ALOX15 P16050 1/20 0.42
HDAC3 O15379 3/20 0.39
HDAC4 P56524 3/20 0.39
HDAC1 Q13547 3/20 0.39
HDAC2 Q92769 3/20 0.39
HDAC8 Q9BY41 3/20 0.39
HDAC6 Q9UBN7 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylonitrile SCHEMBL9249177 0.92 GLA (0.38) TDP1GLAMAPTMAOBCYP1B1
SCHEMBL5146781 0.82 CYP1B1 (0.44) TDP1GLAMAPTMAOBCYP1B1
SCHEMBL27184 0.82 CYP1B1 (0.44) TDP1GLAMAPTMAOBCYP1B1
SCHEMBL1686029 0.81 CYP1B1 (0.43) TDP1GLAMAPTMAOBCYP1B1
SCHEMBL1003800 0.80 CYP1B1 (0.46) TDP1GLAMAPTMAOBCYP1B1
SCHEMBL5161450 0.79 GLA (0.51) TDP1GLAMAPTMAOBCYP1B1
SCHEMBL15255168 0.79 GLA (0.44) TDP1GLAMAPTMAOBCYP1B1
SCHEMBL2729308 0.78 HDAC3 (0.33) HDAC3HDAC4HDAC1HDAC2HDAC8
Styrene SCHEMBL1946755 0.78 ALDH1A1 (0.42) TDP1GLAMAPTMAOBCYP1B1
SCHEMBL353086 0.78 GLA (0.42) TDP1GLAMAPTMAOBCYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030065099-A1 Block copolymers containing hydrogenated vinyl aromatic/(alpha-alkylstyrene) copolymer blocks HAHN STEPHEN F (US) 2003-04-03 US disclosed
WO-2003025026-A1 BLOCK COPOLYMERS CONTAINING HYDROGENATED VINYL AROMATIC/(ALPHA-ALKYLSTYRENE)COPOLYMER BLOCKS DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-27 WO disclosed
EP-1023370-A1 COMPOSITIONS OF INTERPOLYMERS OF ALPHA-OLEFIN MONOMERS WITH ONE OR MORE VINYL OR VINYLIDENE AROMATIC MONOMERS THE DOW CHEMICAL COMPANY (US) 2000-08-02 EP disclosed
WO-1999020685-A1 COMPOSITIONS OF INTERPOLYMERS OF ALPHA-OLEFIN MONOMERS WITH ONE OR MORE VINYL OR VINYLIDENE AROMATIC MONOMERS THE DOW CHEMICAL COMPANY (US) 1999-04-29 WO disclosed