SCHEMBL7060808

SCHEMBL7060808

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nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.62
KDM4E B2RXH2 1/20 0.53
MAPT P10636 1/20 0.53
THRB P10828 1/20 0.53
ALOX15 P16050 1/20 0.53
NFKB1 P19838 1/20 0.53
PTGS2 P35354 1/20 0.53
THPO P40225 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CTSC P53634 1/20 0.43
FOLH1 Q04609 1/20 0.42
MME P08473 4/20 0.39
ENPEP Q07075 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7060803 1.00 ACE (0.62) ACEKDM4EMAPTTHRBALOX15
SCHEMBL16770229 0.97 ACE (0.59) ACEKDM4EMAPTTHRBALOX15
SCHEMBL29380391 0.97 ACE (0.59) ACEKDM4EMAPTTHRBALOX15
SCHEMBL29564528 0.92 ACE (0.54) ACEKDM4EMAPTTHRBALOX15
SCHEMBL30288020 0.92 ACE (0.54) ACEKDM4EMAPTTHRBALOX15
SCHEMBL30287997 0.92 ACE (0.54) ACEKDM4EMAPTTHRBALOX15
SCHEMBL31433262 0.91 ACE (0.53) ACEKDM4EMAPTTHRBALOX15
SCHEMBL30962358 0.89 ACE (0.51) ACEKDM4EMAPTTHRBALOX15
SCHEMBL31139077 0.88 FOLH1 (0.55) ACEKDM4EMAPTTHRBALOX15
SCHEMBL21828667 0.87 ACE (0.65) ACEKDM4EMAPTTHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630064-A1 ALPHA EMITTER LABELLED SOMATOSTATIN RECEPTOR ANTAGONISTS Ariceum Therapeutics GmbH (DE) 2025-10-15 EP claimed
WO-2025043563-A1 PEPTIDE TARGETING SOMATOSTATIN RECEPTOR, DRUG CONJUGATE AND USE THEREOF 主流源生物科技(上海)有限公司 2025-03-06 WO claimed
WO-2024121249-A1 ALPHA EMITTER LABELLED SOMATOSTATIN RECEPTOR ANTAGONISTS ARICEUM THERAPEUTICS GMBH (DE) 2024-06-13 WO claimed
EP-4232097-A1 [161Tb]-BASED RADIOPEPTIDES Universität Basel (CH) 2023-08-30 EP claimed
CN-116406295-A Anti-interleukin 36 receptor (IL-36R) therapy against ichthyosis 安奈普泰斯生物有限公司 2023-07-07 CN claimed
WO-2023051941-A1 [161Tb]-BASED RADIOPEPTIDES UNIVERSITÄT BASEL (CH) 2023-04-06 WO claimed
EP-4684030-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2026-01-28 EP disclosed
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2025-12-02 US disclosed
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-11-06 US disclosed
US-12269837-B2 Bifunctional do2pa derivatives, chelates with metallic cations and use thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2025-04-08 US disclosed
WO-2025043563-A1 PEPTIDE TARGETING SOMATOSTATIN RECEPTOR, DRUG CONJUGATE AND USE THEREOF 主流源生物科技(上海)有限公司 2025-03-06 WO disclosed
WO-2025027145-A1 AGENTS AND METHODS FOR TARGETED DELIVERY TO CELLS BioNTech SE (DE) 2025-02-06 WO disclosed
WO-2025026553-A1 AGENTS AND METHODS FOR TARGETED DELIVERY TO CELLS BioNTech SE (DE) 2025-02-06 WO disclosed
CN-114478789-A anti-PD-L1 and OX40 bispecific antibodies and uses thereof 安徽安科生物工程(集团)股份有限公司 2022-05-13 CN disclosed
US-20220143230-A1 BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-05-12 US disclosed
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME CDRD VENTURES INC. (CA) 2022-04-14 US disclosed
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2022-03-22 US disclosed
WO-2020071258-A1 PROTEIN GLYCATION SUPPRESSANT 味の素株式会社 2020-04-09 WO disclosed
US-20030211078-A1 Therapy for restenosis; antiischemic agents; antitumor agents; anticancer agents; complexing CENTOCOR, INC. 2003-11-13 US disclosed
WO-2003049684-A2 PSEUDO-ANTIBODY CONSTRUCTS CENTOCOR, INC. (US) 2003-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143230-A1 BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF AP2A2, ATP2A2, SLC20A2 ACE 4435/4885KDM4E 3524/4885MAPT 4749/4885
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 ACE 839/4885KDM4E 4069/4885MAPT 4276/4885
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 ACE 836/4885KDM4E 4118/4885MAPT 4302/4885
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS CA9, CA13, CA4 ACE 760/4885KDM4E 2877/4885MAPT 2838/4885
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME GPR119, SSTR5, SSTR2 ACE 839/4885KDM4E 4069/4885MAPT 4276/4885
US-12269837-B2 Bifunctional do2pa derivatives, chelates with metallic cations and use thereof AP2A2, ATP2A2, SLC20A2 ACE 4435/4885KDM4E 3524/4885MAPT 4749/4885
US-20030211078-A1 Therapy for restenosis; antiischemic agents; antitumor agents; anticancer agents; complexing FABP3, FCGR2A, VEGFA ACE 1902/4885KDM4E 4585/4885MAPT 4302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.