SCHEMBL7060915

SCHEMBL7060915

Cc1ccccc1COC(=O)C(CCOS(=O)(=O)c1ccccc1[N+](=O)[O-])OS(=O)(=O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
THRB P10828 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
ALPL P05186 1/20 0.36
ALPI P09923 1/20 0.36
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7065771 0.87 L3MBTL1 (0.47) ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A
SCHEMBL7067318 0.85 AR (0.43) ALDH1A1LMNAMEN1KMT2ANPC1
SCHEMBL7062455 0.84 ALDH1A1 (0.46) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL7062439 0.82 L3MBTL1 (0.40) ALDH1A1LMNAMEN1KMT2ATHRB
SCHEMBL7066685 0.82 KMT2A (0.40) ALDH1A1LMNAMEN1KMT2ATHRB
SCHEMBL7975854 0.81 L3MBTL1 (0.47) ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A
SCHEMBL7064348 0.81 L3MBTL1 (0.43) ALDH1A1LMNAMEN1KMT2ATHRB
SCHEMBL7973313 0.81 L3MBTL1 (0.52) ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A
SCHEMBL7066151 0.81 KMT2A (0.40) ALDH1A1LMNAMEN1KMT2ARAB9A
SCHEMBL7065781 0.80 ALDH1A1 (0.39) ALDH1A1LMNAMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed