SCHEMBL7065771

SCHEMBL7065771

CCOC(=O)C(CCOS(=O)(=O)c1ccccc1[N+](=O)[O-])OS(=O)(=O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
HIF1A Q16665 1/20 0.40
THRB P10828 1/20 0.40
ALDH1A1 P00352 5/20 0.40
PKM P14618 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
GAA P10253 2/20 0.39
F2 P00734 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7975854 0.93 L3MBTL1 (0.47) L3MBTL1KMT2AMEN1HIF1ATHRB
SCHEMBL7973313 0.92 L3MBTL1 (0.52) L3MBTL1KMT2AMEN1HIF1ATHRB
SCHEMBL7062439 0.90 L3MBTL1 (0.40) L3MBTL1KMT2AMEN1THRBALDH1A1
SCHEMBL7062455 0.90 ALDH1A1 (0.46) KMT2AMEN1THRBALDH1A1PKM
SCHEMBL7064348 0.88 L3MBTL1 (0.43) L3MBTL1KMT2AMEN1THRBALDH1A1
SCHEMBL7066685 0.88 KMT2A (0.40) L3MBTL1KMT2AMEN1THRBALDH1A1
SCHEMBL7060915 0.87 ALDH1A1 (0.46) L3MBTL1KMT2AMEN1THRBALDH1A1
SCHEMBL7067318 0.87 AR (0.43) KMT2AMEN1THRBALDH1A1CA1
SCHEMBL7066151 0.86 KMT2A (0.40) KMT2AMEN1THRBALDH1A1CA1
SCHEMBL7064585 0.85 KMT2A (0.40) L3MBTL1KMT2AMEN1THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed