Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | DRD3 | P35462 | 6/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 2/20 | 0.51 |
| ▸ | CCR3 | P51677 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 2/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119593 | 0.92 | CCR3 (0.55) | DRD2DRD3ADRA1ACCR2CCR3 | |
| SCHEMBL7055659 | 0.89 | DRD2 (0.50) | DRD2DRD3ADRA1ACCR2CCR3 | |
| SCHEMBL7057584 | 0.88 | DRD3 (0.69) | DRD2DRD3ADRA1ADRD4 | |
| SCHEMBL7053083 | 0.84 | CCR3 (0.63) | DRD2DRD3ADRA1ACCR3 | |
| Hydrochloric Acid SCHEMBL7058141 | 0.83 | DRD2 (0.53) | DRD2DRD3ADRA1ACCR2CCR3 | |
| SCHEMBL7050625 | 0.83 | DRD2 (0.54) | DRD2DRD3ADRA1ACCR2CCR3 | |
| SCHEMBL7052427 | 0.83 | DRD2 (0.48) | DRD2DRD3ADRA1ACCR2CCR3 | |
| SCHEMBL7052435 | 0.83 | DRD2 (0.48) | DRD2DRD3ADRA1ACCR2CCR3 | |
| Hydrochloric Acid SCHEMBL7055535 | 0.82 | MAPT (0.54) | DRD2DRD3ADRA1ACCR2UBE2M | |
| SCHEMBL7054406 | 0.82 | DRD3 (0.57) | DRD2DRD3ADRA1ACCR3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |