Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052435 | 0.94 | DRD2 (0.48) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7058141 | 0.85 | DRD2 (0.53) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL7119593 | 0.83 | CCR3 (0.55) | DRD2DRD3ADRA1ACCR3CCR2 | |
| SCHEMBL7057584 | 0.83 | DRD3 (0.69) | DRD2DRD3ADRA1A | |
| SCHEMBL7060979 | 0.83 | DRD2 (0.52) | DRD2DRD3ADRA1ACCR3CCR2 | |
| SCHEMBL7055659 | 0.83 | DRD2 (0.50) | DRD2DRD3ADRA1ACCR3CCR2 | |
| SCHEMBL7054406 | 0.81 | DRD3 (0.57) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL7057796 | 0.78 | DRD3 (0.71) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL7053098 | 0.76 | RAB9A (0.53) | DRD2DRD3HTR1AHTR2ACCR3 | |
| SCHEMBL7053551 | 0.76 | DRD2 (0.45) | DRD2DRD3ADRA1AHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |