Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14861314 | 0.85 | MAPT (0.60) | MAPK1POLBCES1MEN1KMT2A | |
| SCHEMBL5778212 | 0.84 | MAPK1 (0.50) | MAPK1POLBCES1MEN1KMT2A | |
| SCHEMBL7062718 | 0.80 | ALDH1A1 (0.50) | MAPK1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7062639 | 0.80 | ALDH1A1 (0.50) | MAPK1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7062015 | 0.79 | RAB9A (0.57) | CES1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL28517308 | 0.79 | MAPK1 (0.55) | MAPK1POLBCES1MEN1KMT2A | |
| SCHEMBL2151529 | 0.79 | MAPK1 (0.55) | MAPK1POLBCES1MEN1KMT2A | |
| SCHEMBL5313733 | 0.79 | MAPK1 (0.56) | MAPK1POLBCES1MEN1KMT2A | |
| SCHEMBL5308303 | 0.78 | MAPK1 (0.47) | MAPK1POLBCES1MEN1KMT2A | |
| SCHEMBL19309854 | 0.78 | MAPK1 (0.55) | MAPK1POLBCES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102746-B1 | SUBSTITUTED PHENYLAMIDINES WITH ANTITHROMBOTIC ACTION | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-05-14 | — | — | EP | disclosed |
| US-6242466-B1 | ANTICOAGULANTS, ANTITUMOR, ANTIMETASTASIS, ANTICARCINOGENIC, AND ANTIINFLAMMATORY AGENTS; BONE DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-05 | — | — | US | disclosed |
| EP-1102746-A1 | SUBSTITUTED PHENYLAMIDINES WITH ANTITHROMBOTIC ACTION | BOEHRINGER INGELHEIM KG (DE) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000005207-A1 | SUBSTITUTED PHENYLAMIDINES WITH ANTITHROMBOTIC ACTION | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-02-03 | — | — | WO | disclosed |