Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048077 | 0.89 | TSHR (0.51) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL31026356 | 0.81 | THRB (0.51) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL10649244 | 0.81 | THRB (0.38) | TSHRTHRBALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL31636160 | 0.79 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL17805629 | 0.79 | CTSK (0.42) | TSHRALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29132462 | 0.79 | THRB (0.44) | TSHRTHRBALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL28175611 | 0.78 | TSHR (0.56) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL31636150 | 0.78 | TSHR (0.60) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11863394 | 0.77 | ALDH1A1 (0.46) | TSHRTHRBALDH1A1TDP1CTSK | |
| SCHEMBL5078251 | 0.77 | TSHR (0.46) | TSHRTHRBALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823458-B1 | POLYMERIC MATERIAL, MEDICAL MATERIAL AND LIQUID POLYMER COMPOSITION | NOF CORP (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-5977257-A | Polymer material, medical material and liquid high molecular composition | NOF CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0823458-A1 | POLYMERIC MATERIAL, MEDICAL MATERIAL AND LIQUID POLYMER COMPOSITION | NOF CORPORATION (JP) | 1998-02-11 | — | — | EP | disclosed |