SCHEMBL7063847

SCHEMBL7063847

COC(=O)CC(NC(=O)OCc1ccccc1)c1cccc(NC(=NC(=O)OCc2ccccc2)NC(=O)OCc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.50
MGLL Q99685 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6958944 0.79 ATM (0.54)
SCHEMBL16201457 0.79 ATM (0.54)
SCHEMBL6650427 0.77 PPARG (0.47) PPARG
SCHEMBL7059602 0.76 ABCB1 (0.39) PPARG
SCHEMBL7061672 0.76 PPARG (0.51) PPARGMGLL
SCHEMBL7059607 0.75 MGLL (0.43) PPARGMGLL
SCHEMBL6648096 0.74 L3MBTL1 (0.51)
SCHEMBL18738533 0.73 POLB (0.49) MGLL
SCHEMBL13029770 0.73 POLB (0.49) MGLL
SCHEMBL7059599 0.73 ABCB1 (0.42) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6617332-B1 Cyclic amidinourea derivatives BAYER AKTIENGESELLSCHAFT (DE) 2003-09-09 US disclosed