SCHEMBL7061674

SCHEMBL7061674

CCOc1cccc2c1Cc1c(cccc1OC)C2

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.46
DRD3 P35462 4/20 0.46
DRD1 P21728 1/20 0.46
DRD5 P21918 1/20 0.46
HTR2A P28223 1/20 0.43
ALDH1A1 P00352 1/20 0.42
DRD4 P21917 2/20 0.42
CYP19A1 P11511 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6899125 0.93 ALDH1A1 (0.47) ALDH1A1
SCHEMBL6905144 0.87 ALDH1A1 (0.49) DRD2DRD3DRD1DRD5ALDH1A1
SCHEMBL6901761 0.87 DRD2 (0.56) DRD2DRD3DRD1DRD5HTR2A
Ammonia Solution, Strong SCHEMBL28116290 0.85 ALDH1A1 (0.47) DRD2DRD3DRD1DRD5ALDH1A1
SCHEMBL6907003 0.81 DRD2 (0.62) DRD2DRD3DRD1DRD5HTR2A
SCHEMBL28263467 0.80 DRD2 (0.67) DRD2DRD3DRD1DRD5HTR2A
Ammonia Solution, Strong SCHEMBL3583671 0.79 DRD2 (0.61) DRD2DRD3DRD1DRD5HTR2A
SCHEMBL7076184 0.78 GAA (0.36) HTR2AALDH1A1
SCHEMBL18489460 0.76 DRD2 (0.50) DRD2DRD3DRD1DRD5HTR2A
SCHEMBL7981436 0.73 ADRA2A (0.41) DRD2DRD3DRD1DRD5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed