Sugi Predict

Sugi Predict / Compounds / SCHEMBL1721087

SCHEMBL1721087

SCHEMBL1721087

Cc1ccc(CBr)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ PYCR1 P32322 1/20 0.44
▸ TDP1 Q9NUW8 2/20 0.42
▸ TP53 P04637 1/20 0.42
▸ TAAR1 Q96RJ0 1/20 0.40
▸ RAB9A P51151 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ LMNA P02545 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ TNF P01375 1/20 0.39
▸ USP2 O75604 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ CASP1 P29466 1/20 0.39
▸ HBB P68871 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ SLC6A2 P23975 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29783360 1.00 ALDH1A1 (0.46) ALDH1A1KDM4EPYCR1TDP1TP53
SCHEMBL233314 0.82 TAAR1 (0.41) ALDH1A1KDM4ETDP1TP53TAAR1
SCHEMBL7061982 0.81 TAAR1 (0.42) ALDH1A1KDM4EPYCR1TDP1TP53
SCHEMBL29712517 0.81 TAAR1 (0.42) ALDH1A1KDM4EPYCR1TDP1TP53
SCHEMBL11856520 0.80 ALDH1A1 (0.48) ALDH1A1KDM4EPYCR1TDP1TP53
SCHEMBL1050239 0.80 TAAR1 (0.56) ALDH1A1KDM4ETDP1TP53TAAR1
SCHEMBL3299248 0.79 PYCR1 (0.47) ALDH1A1KDM4EPYCR1TDP1TP53
SCHEMBL6547406 0.79 TAAR1 (0.48) ALDH1A1KDM4EPYCR1TDP1TP53
SCHEMBL307129 0.78 PYCR1 (0.49) ALDH1A1PYCR1MEN1KMT2AGAA
SCHEMBL10919579 0.78 ESR1 (0.37) ALDH1A1KDM4EPYCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116640106-B Phenylpiperazine compound and preparation method and application thereof 郑州大学 2024-03-08 — — CN claimed
CN-116640106-A Phenylpiperazine compound and preparation method and application thereof 郑州大学 2023-08-25 — — CN claimed
EP-4644373-A1 HYDRAZIDE COMPOUND AND AGRICULTURAL/HORTICULTURAL BACTERICIDAL AGENT Nippon Soda Co., Ltd. (JP) 2025-11-05 — — EP disclosed
WO-2025033011-A1 FIVE-MEMBERED HETEROARYL COMPOUND AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE 日本曹達株式会社 2025-02-13 — — WO disclosed
US-20240270695-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS J. MICHAEL BISHOP INSTITUTE OF CANCER RESEARCH (CN) 2024-08-15 — — US disclosed
WO-2024143336-A1 HYDRAZIDE COMPOUND AND AGRICULTURAL/HORTICULTURAL BACTERICIDAL AGENT 日本曹達株式会社 2024-07-04 — — WO disclosed
CN-116640106-B Phenylpiperazine compound and preparation method and application thereof 郑州大学 2024-03-08 — — CN disclosed
US-11858889-B2 Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease THE TRUSTEES OF INDIANA UNIVERSITY (US) 2024-01-02 — — US disclosed
US-11858951-B2 Boronic acid derivatives MERCK PATENT GMBH (DE) 2024-01-02 — — US disclosed
US-11858951-B2 Boronic acid derivatives MERCK PATENT GMBH (DE) 2024-01-02 — — US disclosed
US-11858951-B2 Boronic acid derivatives MERCK PATENT GMBH (DE) 2024-01-02 — — US disclosed
EP-0038343-A1 SUBSTITUTED CARBOXYLIC CETO-ACIDS, PROCESS FOR THE PREPARATION THEREOF, USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM. BYK GULDEN LOMBERG CHEM FAB (DE) 1981-10-28 — — EP disclosed
EP-0000002-B1 TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1981-08-26 — — EP disclosed
US-4282388-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-08-04 — — US disclosed
EP-0031416-A1 Process for the preparation of substituted benzaldehydes HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1981-07-08 — — EP disclosed
WO-1981001285-A1 SUBSTITUTED CARBOXYLIC CETO-ACIDS,PROCESS FOR THE PREPARATION THEREOF,USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM BYK GULDEN LOMBERG CHEM FAB (DE) 1981-05-14 — — WO disclosed
EP-0002214-B1 BENZYL ETHERS OF CYCLIC 1,2-DIOLS, METHODS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1981-05-13 — — EP disclosed
EP-0002214-A1 Benzyl ethers of cyclic 1,2-diols, methods for their preparation and their use as herbicides BAYER AG (DE) 1979-06-13 — — EP disclosed
US-4146384-A Tetrahydrofuran-ether compounds and herbicidal compositions BAYER AKTIENGESELLSCHAFT (DE) 1979-03-27 — — US disclosed
EP-0000002-A1 Tetrahydrofurane derivatives, processes for their preparation and their use as herbicides BAYER AG (DE) 1978-12-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240270695-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CYP27A1, PNLIP, GOT2 ALDH1A1 461/4885KDM4E 3473/4885PYCR1 764/4885
US-11858889-B2 Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease ADM2, DDAH1, BHMT ALDH1A1 336/4885KDM4E 3545/4885PYCR1 1890/4885
US-11858951-B2 Boronic acid derivatives PSMB7, PSMA7, BRD7 ALDH1A1 3575/4885KDM4E 2171/4885PYCR1 4575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.