Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 15/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066529 | 0.84 | GPR35 (0.77) | GPR35MAOAHPGDALDH1A1LMNA | |
| SCHEMBL9187739 | 0.84 | GPR35 (0.79) | GPR35MAOAHPGDALDH1A1LMNA | |
| SCHEMBL11536342 | 0.80 | MAOA (0.66) | GPR35MAOAHPGDALDH1A1LMNA | |
| SCHEMBL2385579 | 0.72 | GPR35 (0.59) | GPR35MAOAHPGDALDH1A1MAOB | |
| SCHEMBL21316428 | 0.71 | GPR35 (0.58) | GPR35MAOAHPGDALDH1A1LMNA | |
| SCHEMBL22041605 | 0.70 | GPR35 (0.74) | GPR35MAOAHPGDALDH1A1LMNA | |
| SCHEMBL9185867 | 0.69 | MAOB (0.62) | GPR35MAOAHPGDALDH1A1MAOB | |
| SCHEMBL977935 | 0.69 | MAOA (1.00) | GPR35MAOAHPGDALDH1A1LMNA | |
| SCHEMBL982630 | 0.69 | GPR35 (0.72) | GPR35MAOAHPGDALDH1A1LMNA | |
| SCHEMBL9587791 | 0.69 | GPR35 (0.77) | GPR35MAOAHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030219755-A1 | Compositions and methods for performing hybridization assays using target enhanced signal amplification (TESA) | APPLIED GENE TECHNOLOGIES, INC. | 2003-11-27 | — | — | US | claimed |
| US-20030219755-A1 | Compositions and methods for performing hybridization assays using target enhanced signal amplification (TESA) | APPLIED GENE TECHNOLOGIES, INC. | 2003-11-27 | — | — | US | disclosed |
| US-5026840-A | For hybridization assays | MOLECULAR DIAGNOSTICS, INC. (US) | 1991-06-25 | — | — | US | disclosed |
| US-4950744-A | FOR HYBRIDIZATION ASSAYS; PROBES | MOLECULAR DIAGNOSTICS, INC. (US) | 1990-08-21 | — | — | US | disclosed |