Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065942 | 0.87 | MAPT (0.44) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL7064614 | 0.87 | MAPT (0.44) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL7065963 | 0.85 | MAPT (0.38) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL914349 | 0.83 | DHODH (0.41) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL7062256 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL7064608 | 0.81 | MAPT (0.44) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL7065388 | 0.81 | ATM (0.38) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL7062984 | 0.80 | MAPT (0.33) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL7062996 | 0.79 | MAPT (0.38) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL7064666 | 0.79 | KMT2A (0.38) | ALDH1A1MAPTLMNAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313461-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | Melacure Therapeutics AB (SE) | 2003-05-28 | — | — | EP | claimed |
| WO-2002011715-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | MELACURE THERAPEUTICS AB (SE) | 2002-02-14 | — | — | WO | claimed |