Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066436 | 0.91 | CA2 (0.46) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL7065198 | 0.84 | ATM (0.45) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL7065861 | 0.83 | MAPT (0.53) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL914349 | 0.83 | DHODH (0.41) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL7065963 | 0.80 | MAPT (0.38) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| SCHEMBL7065078 | 0.79 | ERN1 (0.41) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL7062480 | 0.79 | ALDH1A1 (0.47) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL7065942 | 0.79 | MAPT (0.44) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL7064614 | 0.79 | MAPT (0.44) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL7064657 | 0.79 | MAPT (0.41) | KMT2AMAPTMEN1GAANCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313461-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | Melacure Therapeutics AB (SE) | 2003-05-28 | — | — | EP | claimed |
| WO-2002011715-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | MELACURE THERAPEUTICS AB (SE) | 2002-02-14 | — | — | WO | claimed |