Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 7/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062256 | 0.84 | ALDH1A1 (0.41) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL7062982 | 0.83 | CYP2D6 (0.34) | MAPTALDH1A1CYP2D6MEN1KMT2A | |
| SCHEMBL7062981 | 0.83 | CYP2D6 (0.34) | MAPTALDH1A1CYP2D6MEN1KMT2A | |
| SCHEMBL7062996 | 0.81 | MAPT (0.38) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL7065388 | 0.81 | ATM (0.38) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL7062480 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL7065577 | 0.79 | ALDH1A1 (0.37) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7066729 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL7065963 | 0.79 | MAPT (0.38) | MAPTALDH1A1CYP2C9CYP1A2MEN1 | |
| SCHEMBL7066015 | 0.78 | KMT2A (0.38) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313461-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | Melacure Therapeutics AB (SE) | 2003-05-28 | — | — | EP | claimed |
| WO-2002011715-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | MELACURE THERAPEUTICS AB (SE) | 2002-02-14 | — | — | WO | claimed |