Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15525622 | 0.81 | ALDH1A1 (0.33) | LMNAPKMSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8411178 | 0.78 | MEN1 (0.32) | MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL2788715 | 0.71 | MEN1 (0.33) | LMNAPKMSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL3373110 | 0.71 | MEN1 (0.33) | LMNAPKMSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7062104 | 0.71 | ALDH1A1 (0.35) | LMNAPKMSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL668173 | 0.69 | MEN1 (0.34) | LMNAPKMSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL15568368 | 0.68 | MEN1 (0.33) | LMNAPKMSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7062638 | 0.68 | BRD4 (0.37) | MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL19436423 | 0.68 | ALDH1A1 (0.34) | MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL3067513 | 0.63 | ALDH1A1 (0.39) | SMN1; SMN2MEN1ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311505-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE ( NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS ) | PHARMACIA & UPJOHN COMPANY (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002016355-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC) ACETYLCHOLINE RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |