Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15525622 | 0.81 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL2788715 | 0.78 | MEN1 (0.33) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL7062683 | 0.78 | LMNA (0.32) | MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL668173 | 0.69 | MEN1 (0.34) | MEN1ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL15568368 | 0.68 | MEN1 (0.33) | MEN1ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL3373110 | 0.68 | MEN1 (0.33) | MEN1ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL7062104 | 0.68 | ALDH1A1 (0.35) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL19436423 | 0.68 | ALDH1A1 (0.34) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL7062638 | 0.65 | BRD4 (0.37) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL3067513 | 0.63 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994394-A | Polyheterocyclic compounds | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1999-11-30 | — | — | US | disclosed |
| EP-0866066-A1 | Polyheterocyclic compounds | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1998-09-23 | — | — | EP | disclosed |