Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411178 | 0.81 | MEN1 (0.32) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7062683 | 0.81 | LMNA (0.32) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL2788715 | 0.74 | MEN1 (0.33) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL668173 | 0.71 | MEN1 (0.34) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL15568368 | 0.70 | MEN1 (0.33) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL3373110 | 0.70 | MEN1 (0.33) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL19436423 | 0.70 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL7062104 | 0.70 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL2790000 | 0.68 | SPHK2 (0.34) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7062638 | 0.67 | BRD4 (0.37) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377862-A | Metal-based complexes as photodynamic compounds and use thereof | MCFARLAND SHERRI ANN | 2016-03-02 | — | — | CN | disclosed |
| CN-105120957-A | Metal-based thiophene photodynamic compounds and uses thereof | MCFARLAND SHERRI | 2015-12-02 | — | — | CN | disclosed |
| EP-2854948-A1 | METAL-BASED THIOPHENE PHOTODYNAMIC COMPOUNDS AND THEIR USE | Theralase, Inc. (CA) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013158550-A1 | METAL-BASED THIOPHENE PHOTODYNAMIC COMPOUNDS AND THEIR USE | THERALASE, INC. (CA) | 2013-10-24 | — | — | WO | disclosed |