Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 16/20 | 0.55 |
| ▸ | MGLL | Q99685 | 5/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059883 | 0.93 | FAAH (0.53) | FAAHSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7121391 | 0.82 | FAAH (0.41) | FAAHSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27995321 | 0.77 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11800230 | 0.74 | TSHR (0.64) | FAAHMGLLSLC6A3 | |
| Acetic Acid SCHEMBL28974131 | 0.72 | TSHR (0.60) | FAAHMGLLSLC6A3 | |
| SCHEMBL21706782 | 0.72 | FAAH (0.54) | FAAHMGLLSLC6A3 | |
| SCHEMBL27741870 | 0.72 | FAAH (0.54) | FAAHMGLLSLC6A3 | |
| SCHEMBL1873958 | 0.72 | SLC6A3 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1878142 | 0.72 | SLC6A3 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4677228 | 0.71 | EPHX2 (0.49) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874818-B1 | NOVEL SUBSTITUTED ARYL COMPOUNDS USEFUL AS MODULATORS OF ACETYLCHOLINE RECEPTORS | MERCK & CO INC (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6316490-B1 | FOR THERAPY OF PARKINSON'S DISEASE, ALZHEIMER'S DISEASE, DEMENTIA, CONTROLLING PAIN | MERCK & CO., INC. | 2001-11-13 | — | — | US | disclosed |