Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.68 |
| ▸ | CA2 | P00918 | 3/20 | 0.68 |
| ▸ | CA7 | P43166 | 3/20 | 0.68 |
| ▸ | CA9 | Q16790 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397022 | 0.88 | CA1 (0.78) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL8640883 | 0.84 | CA1 (0.61) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL7153591 | 0.84 | CA1 (0.76) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL23258692 | 0.82 | CA1 (0.70) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL218661 | 0.82 | CA1 (0.70) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL508126 | 0.82 | CA1 (0.70) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL122306 | 0.82 | CA1 (0.70) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL16269805 | 0.82 | CA1 (0.70) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL16633105 | 0.81 | CA1 (0.73) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL3647026 | 0.81 | CA1 (0.68) | CA1CA2CA7CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030236229-A1 | Novel 3,5,and/or 6 substituted analogues of swainsonine processes for their preparation and their use as therapeutic agents | GLYCODESIGN INC. (CA) | 2003-12-25 | — | — | US | disclosed |
| US-20020099065-A1 | Novel 3, 5, and/or 6 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents | GLYCODESIGN INC. (CA) | 2002-07-25 | — | — | US | disclosed |
| CN-1251588-A | Novel 3,5 and/or 6 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents | GLYCODESIGN INC (CA) | 2000-04-26 | — | — | CN | disclosed |
| US-6048870-A | MANNOSIDASE INHIBITOR; IMMUNOSTIMULANT | GLYCODESIGN (CA) | 2000-04-11 | — | — | US | disclosed |
| EP-0934318-A1 | NOVEL 3, 5, AND/OR 6 SUBSTITUTED ANALOGUES OF SWAINSONINE, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS THERAPEUTIC AGENTS | Glycodesign Inc. (CA) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998014446-A1 | NOVEL 3, 5, AND/OR 6 SUBSTITUTED ANALOGUES OF SWAINSONINE, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS THERAPEUTIC AGENTS | GLYCODESIGN INC. (CA) | 1998-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236229-A1 | Novel 3,5,and/or 6 substituted analogues of swainsonine processes for their preparation and their use as therapeutic agents | WDR77, WDR3, WDR5 | CA1 4516/4885CA2 4653/4885CA7 4152/4885 |
| US-20020099065-A1 | Novel 3, 5, and/or 6 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents | WDR5, WDR3, WDR77 | CA1 4624/4885CA2 4686/4885CA7 4347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.