Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.64 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.64 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.64 |
| ▸ | CDK2 | P24941 | 3/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | AHCY | P23526 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999274 | 0.84 | CDK1 (0.45) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL3441002 | 0.84 | CDK1 (0.54) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL30586349 | 0.84 | CCNE1 (0.45) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL7057757 | 0.84 | CCNE1 (0.45) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL30586395 | 0.84 | HSP90AA1 (0.48) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL2054791 | 0.84 | HSP90AB1 (0.52) | HSP90AA1HSP90AB1 | |
| SCHEMBL27516653 | 0.81 | CCNE1 (0.70) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL24709725 | 0.80 | CCNE1 (0.72) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL21137280 | 0.80 | CCNE1 (0.72) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL1798270 | 0.79 | ADORA2A (0.72) | ADORA2AAHCYADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097939-B1 | Method for the synthesis of isoguanosine and of its 2'-derivatives | BAYER AG (US) | 2004-02-11 | — | — | EP | disclosed |
| EP-0778898-B1 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | BAYER AG (US) | 2002-11-13 | — | — | EP | disclosed |
| US-20010026918-A1 | Reduction of nonspecific hybridization by using novel base-pairing schemes | COLLINS MARK L (US) | 2001-10-04 | — | — | US | disclosed |
| US-6232462-B1 | SYNTHESIS OF AN ISOGUANOSINE DERIVATIVE USED AS ANTISENSE AND APTAMER THERAPEUTICS AND DRUG DISCOVERY | BAYER CORPORATION | 2001-05-15 | — | — | US | disclosed |
| EP-1097939-A2 | Method for the synthesis of isoguanosine and its 2'-derivatives | Bayer Corporation (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-1996006950-A9 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | — | 1997-05-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010026918-A1 | Reduction of nonspecific hybridization by using novel base-pairing schemes | UNG, SAMHD1, RNGTT | CDK1 3625/4885CCNB1 3099/4885CCNE1 3075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.