SCHEMBL7063178

SCHEMBL7063178

O=C(Oc1ccc(Cl)cc1)C(=O)Oc1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.50
LIPE Q05469 4/20 0.48
HPGD P15428 1/20 0.48
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPT P10636 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
PPARA Q07869 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HTT P42858 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
BCHE P06276 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6202766 0.89 HPGD (0.66) ELANEHPGDCYP11B1CYP11B2MEN1
SCHEMBL7063314 0.89 HPGD (0.50) ELANELIPEHPGDCYP11B1CYP11B2
SCHEMBL8663497 0.88 MEN1 (0.47) ELANELIPEHPGDCYP11B1CYP11B2
SCHEMBL8465167 0.88 LIPE (0.49) ELANELIPEHPGDCYP11B1CYP11B2
SCHEMBL3870416 0.86 KMT2A (0.49) ELANELIPEHPGDCYP11B1CYP11B2
SCHEMBL5320836 0.86 ELANE (0.44) ELANELIPEHPGDCYP11B1CYP11B2
SCHEMBL56865 0.84 KMT2A (0.50) ELANELIPEHPGDCYP11B1CYP11B2
SCHEMBL11122466 0.83 ELANE (0.42) ELANELIPEHPGDCYP11B1CYP11B2
SCHEMBL452065 0.83 ELANE (0.59) ELANELIPEHPGDCYP11B1CYP11B2
SCHEMBL9575359 0.83 ELANE (0.42) ELANELIPEHPGDCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5389302-A Fluorescent dye and hydrogen peroxide; detects cracks or flaws in surface; oxalate ester or amide developer ROCKWELL INTERNATIONAL CORPORATION (US) 1995-02-14 US claimed
CN-218502269-U Bipyramid desiccator is used in preparation of p chlorobenzene alcohol oxalic acid diester 青岛和兴精细化学有限公司 2023-02-21 CN disclosed
EP-3189029-B1 METHOD OF MELT POLYMERIZING POLYCARBONATE AND THE POLYCARBONATE MADE THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-02-20 EP disclosed
EP-2970096-B1 PROCESS FOR PURIFICATION OF DIPHENYL CARBONATE FOR THE MANUFACTURING OF HIGH QUALITY POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-08-08 EP disclosed
EP-2816068-B1 Process for the manufacture of polycarbonate compositions SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-12-27 EP disclosed
US-20170306090-A1 METHOD FOR MAKING POLYCARBONATE USING A LIQUID KETONE MIXTURE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-10-26 US disclosed
EP-3215551-A1 METHOD FOR MAKING POLYCARBONATE USING A LIQUID KETONE MIXTURE SABIC Global Technologies B.V. (NL) 2017-09-13 EP disclosed
US-9738590-B1 Method of melt polymerizing polycarbonate and the polycarbonate made therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-22 US disclosed
US-20170233328-A1 METHOD OF MELT POLYMERIZING POLYCARBONATE AND THE POLYCARBONATE MADE THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-17 US disclosed
US-9732028-B2 Process for purification of diphenyl carbonate for the manufacturing of high quality polycarbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-15 US disclosed
EP-0834496-A1 Preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-04-08 EP disclosed
EP-0834495-A1 Process for preparing diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-04-08 EP disclosed
US-5731453-A Process for producing a diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
EP-0826658-A1 Catalyst for decarbonylation reaction UBE INDUSTRIES, LTD. (JP) 1998-03-04 EP disclosed
EP-0814074-A1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES, LTD. (JP) 1997-12-29 EP disclosed
EP-0795539-A1 Process for producing a diaryl carbonate UBE INDUSTRIES LIMITED (JP) 1997-09-17 EP disclosed
US-5648510-A DECARBONYLATION OF OXALATE UBE INDUSTRIES, LTD. (JP) 1997-07-15 US disclosed
EP-0737665-A1 Process for preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1996-10-16 EP disclosed
US-5389302-A Fluorescent dye and hydrogen peroxide; detects cracks or flaws in surface; oxalate ester or amide developer ROCKWELL INTERNATIONAL CORPORATION (US) 1995-02-14 US disclosed
US-4031165-A BLOCK COPOLYMER TEIJIN LIMITED (JA) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233328-A1 METHOD OF MELT POLYMERIZING POLYCARBONATE AND THE POLYCARBONATE MADE THEREFROM PHF2, CYP21A2, HSD11B2 ELANE 2769/4885LIPE 3700/4885HPGD 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.