SCHEMBL8663497

SCHEMBL8663497

O=C(O)C(=O)Oc1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
PPARA Q07869 2/20 0.47
MAPT P10636 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
ELANE P08246 1/20 0.46
TAAR1 Q96RJ0 1/20 0.45
LIPE Q05469 2/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
HPGD P15428 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7063178 0.88 ELANE (0.50) MEN1KMT2APPARAMAPTCYP1A2
Ammonia Solution, Strong SCHEMBL20819414 0.85 ELANE (0.42) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL8465167 0.82 LIPE (0.49) MEN1KMT2APPARAMAPTCYP1A2
SCHEMBL292790 0.81 ELANE (0.53) MEN1KMT2APPARAMAPTCYP1A2
SCHEMBL5320836 0.80 ELANE (0.44) MEN1KMT2APPARAMAPTCYP1A2
SCHEMBL3870416 0.80 KMT2A (0.49) MEN1KMT2APPARAMAPTCYP1A2
Hydrochloric Acid SCHEMBL11850724 0.79 ELANE (0.52) MEN1KMT2APPARAMAPTCYP1A2
SCHEMBL1463536 0.79 MEN1 (0.46) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL27467310 0.79 ELANE (0.52) MEN1KMT2APPARAMAPTCYP1A2
SCHEMBL13274370 0.78 HPGD (0.46) MEN1KMT2APPARAMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811573-A Process for producing a diaryl carnonate UBE INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed
CN-1181374-A Preparation of diaryl carbonate UBE INDUSTRIES (JP) 1998-05-13 CN disclosed