SCHEMBL7063327

SCHEMBL7063327

C=C(C#N)C(=O)OC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064534 0.94 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL7199627 0.87 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL9009023 0.82 THRB (0.33)
SCHEMBL8447490 0.79 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL1444151 0.79 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL15157588 0.79 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL15157375 0.79 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL1444292 0.79 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL15156807 0.79 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL11649523 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6607631-B1 Polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an CLOSURE MEDICAL CORPORATION 2003-08-19 US claimed
WO-2002020684-A2 ADHESIVE COMPOSITIONS WITH REDUCED COEFFICIENT OF FRICTION CLOSURE MEDICAL CORPORATION (US) 2002-03-14 WO claimed
US-6607631-B1 Polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an CLOSURE MEDICAL CORPORATION 2003-08-19 US disclosed
WO-2002020684-A2 ADHESIVE COMPOSITIONS WITH REDUCED COEFFICIENT OF FRICTION CLOSURE MEDICAL CORPORATION (US) 2002-03-14 WO disclosed