SCHEMBL7063333

SCHEMBL7063333

[O-][S+](CCc1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
MAOA P21397 4/20 0.38
MAOB P27338 4/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
ATM Q13315 1/20 0.37
KEAP1 Q14145 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13975646 0.87 SIGMAR1 (0.43) SMN1; SMN2HTR2AMAOAMAOBSIGMAR1
SCHEMBL4612912 0.86 ALDH1A1 (0.35) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL7063604 0.86 L3MBTL1 (0.41) ALDH1A1TDP1ATMNPC1LMNA
SCHEMBL1314975 0.83 CYP3A4 (0.38) ALDH1A1TDP1CYP3A4CALM1
SCHEMBL20921242 0.83 CYP3A4 (0.38) ALDH1A1TDP1CYP3A4CALM1
SCHEMBL21258375 0.82 ESRRG (0.44) CA1CA2SIGMAR1NPC1KDM1A
SCHEMBL29182302 0.79 TP53 (0.40) ALDH1A1TDP1SMN1; SMN2SIGMAR1CYP3A4
SCHEMBL776216 0.79 TP53 (0.40) ALDH1A1TDP1SMN1; SMN2SIGMAR1CYP3A4
SCHEMBL30828031 0.79 TP53 (0.40) ALDH1A1TDP1SMN1; SMN2SIGMAR1CYP3A4
SCHEMBL349504 0.78 ALDH1A1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed
US-4656290-A Process for preparing thio, dithio or carbonyl compounds CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1987-04-07 US disclosed