Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.41 |
| ▸ | CA1 | P00915 | 13/20 | 0.40 |
| ▸ | CA9 | Q16790 | 10/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.37 |
| ▸ | ITGAL | P20701 | 2/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098906 | 0.86 | PTGS1 (0.43) | CA2CA1CA9CA12PTGS1 | |
| SCHEMBL8107826 | 0.83 | CA2 (0.42) | CA2CA1CA9CA12PTGS1 | |
| SCHEMBL8100682 | 0.82 | PTGES2 (0.42) | CA2CA1CA9CA12PTGS1 | |
| SCHEMBL4575696 | 0.81 | PTGS1 (0.56) | CA2CA1CA9CA12PTGS1 | |
| SCHEMBL7063507 | 0.80 | CA2 (0.44) | CA2CA1CA9CA12PTGS1 | |
| SCHEMBL8101068 | 0.78 | PTGS1 (0.43) | CA2CA1CA9CA12PTGS1 | |
| SCHEMBL8107827 | 0.77 | CA2 (0.48) | CA2CA1CA9CA12PTGS1 | |
| SCHEMBL7067324 | 0.76 | CA2 (0.41) | CA2CA1CA9CA12PTGS1 | |
| SCHEMBL8099469 | 0.76 | CA2 (0.63) | CA2CA1CA9PTGS1PTGS2 | |
| SCHEMBL8481841 | 0.76 | CA2 (0.63) | CA2CA1CA9PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968180-B1 | SUBSTITUTED DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLOOXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2003-06-04 | — | — | EP | claimed |
| EP-0968180-B1 | SUBSTITUTED DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLOOXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2003-06-04 | — | — | EP | disclosed |
| EP-0968180-A1 | SUBSTITUTED DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLOOXYGENASE II | Nycomed Austria GmbH (AT) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033769-A1 | SUBSTITUTED DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLOOXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 1998-08-06 | — | — | WO | disclosed |