Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063657 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EMEN1P2RY12MAPT | |
| SCHEMBL5849764 | 0.84 | P2RY12 (0.69) | ALDH1A1KDM4EMEN1P2RY12MAPT | |
| SCHEMBL5849588 | 0.84 | P2RY12 (0.68) | ALDH1A1KDM4EMEN1P2RY12KMT2A | |
| SCHEMBL5848640 | 0.84 | KIT (0.51) | ALDH1A1KDM4EMEN1P2RY12MAPT | |
| SCHEMBL7062965 | 0.80 | MEN1 (0.56) | ALDH1A1KDM4EMEN1P2RY12MAPT | |
| SCHEMBL7063546 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4EMEN1P2RY12MAPT | |
| SCHEMBL7064496 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1P2RY12MAPT | |
| SCHEMBL7060963 | 0.77 | MEN1 (0.78) | ALDH1A1KDM4EMEN1P2RY12MAPT | |
| SCHEMBL7059713 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4EMEN1P2RY12MAPT | |
| SCHEMBL7062128 | 0.76 | KDM4E (0.83) | ALDH1A1KDM4EMEN1P2RY12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153556-A1 | Piperazine and homopiperazine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153556-A1 | Piperazine and homopiperazine compounds | HAMP, MPL, F2 | ALDH1A1 3346/4885KDM4E 2962/4885MEN1 2603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.