Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279027 | 0.85 | HSD17B10 (0.47) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL7122749 | 0.82 | TDP1 (0.55) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL8373001 | 0.82 | TSHR (0.55) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL7783341 | 0.80 | CYP1A2 (0.60) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL28641504 | 0.80 | TDP1 (0.53) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL10034862 | 0.79 | TDP1 (0.57) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL460989 | 0.79 | HTT (0.66) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL21660553 | 0.79 | TDP1 (0.49) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL28450772 | 0.79 | HSPB1 (0.43) | TDP1ALDH1A1TSHRHTTHSD17B10 | |
| SCHEMBL10411133 | 0.79 | ALDH1A1 (0.42) | TDP1ALDH1A1CYP3A4TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313750-A1 | METHOD FOR PRODUCING WATER-SOLUBLE SACCHARIDE CONJUGATES AND SACCHARIDE MIMETICS BY DIELS-ALDER REACTION | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016378-A1 | METHOD FOR PRODUCING WATER-SOLUBLE SACCHARIDE CONJUGATES AND SACCHARIDE MIMETICS BY DIELS-ALDER REACTION | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2002-02-28 | — | — | WO | disclosed |