Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132981 | 0.80 | PDK2 (0.32) | HTR6 | |
| SCHEMBL6917029 | 0.76 | HTR6 (0.33) | HTR6HTR2ACYP2D6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8383629 | 0.74 | POLB (0.33) | HTR6CYP2D6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8379366 | 0.74 | KDM4E (0.35) | HTR6HTR2ACYP2D6SIGMAR1 | |
| SCHEMBL7642875 | 0.74 | HTR6 (0.32) | HTR6SIGMAR1 | |
| SCHEMBL8380999 | 0.74 | HTR2A (0.38) | HTR6HTR2ACYP2D6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8382919 | 0.72 | SIGMAR1 (0.32) | HTR6CYP2D6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8379097 | 0.72 | HTR6 (0.31) | HTR6HTR2A | |
| SCHEMBL8559397 | 0.72 | HTR6 (0.33) | HTR6HTR2ACYP2D6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7645798 | 0.72 | HTR2A (0.36) | HTR6HTR2ACYP2D6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530908-B2 | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM NV (NL) | 2003-06-04 | — | — | EP | disclosed |
| EP-0530908-B1 | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM NV (NL) | 1999-04-21 | — | — | EP | disclosed |
| EP-0530908-A1 | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM N.V. (NL) | 1993-03-10 | — | — | EP | disclosed |