SCHEMBL6917029

SCHEMBL6917029

C[SiH](C)[Hf](C1C=Cc2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
SIGMAR1 Q99720 2/20 0.31
GPR3 P46089 1/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7642875 0.98 HTR6 (0.32) HTR6SIGMAR1GPR3
SCHEMBL29702331 0.87 HTR2A (0.34) HTR6SIGMAR1KDM4ELMNATP53
SCHEMBL6473076 0.87 HTR2A (0.34) HTR6SIGMAR1KDM4ELMNATP53
SCHEMBL1242110 0.87 HTR2A (0.34) HTR6SIGMAR1KDM4ELMNATP53
Hydrochloric Acid SCHEMBL9069305 0.85 HTR2A (0.33) HTR6SIGMAR1KDM4ELMNATP53
Hydrochloric Acid SCHEMBL2135928 0.85 HTR2A (0.33) HTR6SIGMAR1KDM4ELMNATP53
SCHEMBL6916996 0.79 GPR3 (0.41) GPR3LMNACHRM2CYP2D6CHRM1
Hydrochloric Acid SCHEMBL6434708 0.77 GPR3 (0.40) GPR3CHRM2CYP2D6CHRM1SLC6A2
Ethylene SCHEMBL7063941 0.76 HTR6 (0.35) HTR6SIGMAR1CYP2D6HTR2A
SCHEMBL30487865 0.74 SIGMAR1 (0.33) HTR6SIGMAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0868445-B1 HIGH TEMPERATURE OLEFIN POLYMERIZATION PROCESS EXXONMOBIL CHEM PATENTS INC (US) 2002-02-27 EP claimed
EP-0927201-B1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO LTD (KR) 2004-04-14 EP disclosed
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed