Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23859850 | 0.89 | L3MBTL1 (0.46) | CTSKL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL23859851 | 0.89 | L3MBTL1 (0.46) | CTSKL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL27438723 | 0.87 | ATM (0.41) | CTSKL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL11566665 | 0.82 | HDAC3 (0.41) | CTSKL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL7280562 | 0.81 | L3MBTL1 (0.39) | CTSKL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL28365893 | 0.81 | L3MBTL1 (0.39) | CTSKL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL7273178 | 0.81 | L3MBTL1 (0.39) | CTSKL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL28365896 | 0.81 | L3MBTL1 (0.39) | CTSKL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL4277566 | 0.80 | CTSS (0.46) | CTSK | |
| SCHEMBL29226532 | 0.80 | PPARG (0.41) | CTSKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313696-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018323-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |