SCHEMBL7064561

SCHEMBL7064561

Cc1ccccc1OC(=O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.50
TDP1 Q9NUW8 4/20 0.46
ATM Q13315 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
BCHE P06276 1/20 0.46
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
NOTUM Q6P988 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HTT P42858 2/20 0.42
TSHR P16473 2/20 0.41
ESR1 P03372 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
HMGB1 P09429 1/20 0.41
HPGD P15428 1/20 0.41
GGT1 P19440 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064558 0.89 TDP1 (0.50) PPARGTDP1ATML3MBTL1BCHE
SCHEMBL7553873 0.85 AKR1C3 (0.42) PPARGTDP1ATMBCHERXRA
SCHEMBL27420545 0.84 TDP1 (0.47) PPARGTDP1ATML3MBTL1BCHE
SCHEMBL6537089 0.84 POLB (0.54) PPARGTDP1L3MBTL1KDM4EALDH1A1
SCHEMBL28140943 0.84 TDP1 (0.47) PPARGTDP1ATML3MBTL1BCHE
SCHEMBL6363008 0.83 TDP1 (0.46) PPARGTDP1ATML3MBTL1BCHE
SCHEMBL577353 0.83 PPARG (0.53) PPARGTDP1ATML3MBTL1BCHE
SCHEMBL7553864 0.82 FABP4 (0.44) PPARGTDP1ATML3MBTL1SMN1; SMN2
SCHEMBL650229 0.82 ELANE (0.50) PPARGTDP1ATML3MBTL1BCHE
SCHEMBL21551645 0.82 ATM (0.45) PPARGTDP1ATML3MBTL1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9174918-B2 Process for preparing diaryl oxalate UBE INDUSTRIES, LTD. (JP) 2015-11-03 US disclosed
US-20120296063-A1 PROCESS FOR PREPARING DIARYL OXALATE UBE CORPORATION (JP) 2012-11-22 US disclosed
CN-1583708-A Catalytic synthesis of phenyloxalate and methyl phenyl oxalate UNIV TIANJIN (CN) 2005-02-23 CN disclosed
EP-1013633-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2003-05-28 EP disclosed
EP-0832910-B1 Process for producing a polycarbonate UBE INDUSTRIES (JP) 2002-06-26 EP disclosed
EP-0832872-B1 Process for producing diaryl carbonate UBE INDUSTRIES (JP) 2002-01-30 EP disclosed
EP-0795539-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2001-10-31 EP disclosed
EP-0814074-B1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES (JP) 2001-03-28 EP disclosed
EP-1013633-A1 Process for producing a diaryl carbonate Ube Industries, Ltd. (JP) 2000-06-28 EP disclosed
US-6018072-A SUBJECTING AN ALKYLARYL OXALATE TO A DISPROPORTIONATION REACTION IN THE PRESENCE OF A DISPROPORTIONATION CATALYST TO PRODUCE A DIARYL OXALATE WHILE REMOVING A DIALKYL OXALATE BY-PRODUCT UBE INDUSTRIES, LTD. (JP) 2000-01-25 US disclosed
US-5922827-A Process for producing a polycarbonate UBE INDUSTRIES, LTD. (JP) 1999-07-13 US disclosed
US-5834615-A Process for producing diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-11-10 US disclosed
US-5811573-A Process for producing a diaryl carnonate UBE INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed
EP-0832910-A2 Process for producing a polycarbonate UBE INDUSTRIES, LTD. (JP) 1998-04-01 EP disclosed
EP-0832872-A1 Process for producing diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-04-01 EP disclosed
US-5731453-A Process for producing a diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
US-5705677-A Diphenyl oxalate-phenol adduct, process for producing the adduct and method of producing diphenyl oxalate from the adduct UBE INDUSTRIES, LTD. (JP) 1998-01-06 US disclosed
EP-0814074-A1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES, LTD. (JP) 1997-12-29 EP disclosed
EP-0795539-A1 Process for producing a diaryl carbonate UBE INDUSTRIES LIMITED (JP) 1997-09-17 EP disclosed
EP-0776882-A1 Diphenyl oxalate-phenol adduct, process for producing the adduct and method of producing diphenyl oxalate from the adduct UBE INDUSTRIES, LTD. (JP) 1997-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120296063-A1 PROCESS FOR PREPARING DIARYL OXALATE TH, CYP2E1, ADH1A PPARG 3074/4885TDP1 604/4885ATM 1695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.