Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064561 | 0.84 | PPARG (0.50) | TDP1ATML3MBTL1PPARGBCHE | |
| SCHEMBL7064558 | 0.81 | TDP1 (0.50) | TDP1ATML3MBTL1PPARGBCHE | |
| SCHEMBL3527866 | 0.81 | CA1 (0.50) | ATML3MBTL1BCHERXRASMN1; SMN2 | |
| SCHEMBL577353 | 0.79 | PPARG (0.53) | TDP1ATML3MBTL1PPARGBCHE | |
| SCHEMBL7058523 | 0.79 | TDP1 (0.46) | TDP1ATML3MBTL1PPARGBCHE | |
| SCHEMBL28887341 | 0.79 | ALDH1A1 (0.49) | TDP1ATML3MBTL1PPARGSMN1; SMN2 | |
| SCHEMBL650229 | 0.78 | ELANE (0.50) | TDP1ATML3MBTL1PPARGBCHE | |
| SCHEMBL10954450 | 0.78 | GAA (0.45) | SMN1; SMN2KDM4EALDH1A1TSHRESR1 | |
| SCHEMBL7994148 | 0.78 | TDP1 (0.45) | TDP1ATML3MBTL1PPARGBCHE | |
| SCHEMBL1922158 | 0.78 | L3MBTL1 (0.44) | ATML3MBTL1SMN1; SMN2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1095716-A | Novel compound having excellent hypoglycemic activity | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | CN | disclosed |