SCHEMBL7064586

SCHEMBL7064586

Cc1ccc(C(C)N2CCC2C(=O)OCCc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 12/20 0.48
CHRM2 P08172 3/20 0.42
CHRM4 P08173 3/20 0.42
CHRM5 P08912 3/20 0.42
CHRM1 P11229 3/20 0.42
CHRM3 P20309 3/20 0.42
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066527 0.93 FKBP1A (0.46) FKBP1ACHRM2CHRM4CHRM5CHRM1
SCHEMBL7067284 0.90 FKBP1A (0.51) FKBP1ACHRM2CHRM4CHRM5CHRM1
SCHEMBL7068394 0.89 FKBP1A (0.51) FKBP1ACHRM2CHRM4CHRM5CHRM1
SCHEMBL7066507 0.89 FKBP1A (0.47) FKBP1A
SCHEMBL7067280 0.83 ALDH1A1 (0.45)
SCHEMBL7066206 0.83 FKBP1A (0.40) FKBP1ACHRM2CHRM4CHRM5CHRM1
SCHEMBL7064400 0.81 FKBP1A (0.50) FKBP1A
SCHEMBL7062864 0.81 FKBP1A (0.40) FKBP1ACHRM2CHRM4CHRM5CHRM1
SCHEMBL7062112 0.81 ALDH1A1 (0.53) CHRM2CHRM1
SCHEMBL7067151 0.80 GAA (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed