Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066103 | 0.90 | ALDH1A1 (0.48) | ALDH1A1LMNAKMT2AHSD11B1POLB | |
| SCHEMBL7062112 | 0.89 | ALDH1A1 (0.53) | ALDH1A1LMNAKMT2AGAAKDM4E | |
| SCHEMBL7066206 | 0.89 | FKBP1A (0.40) | ALDH1A1LMNAKMT2ATSHRNPC1 | |
| SCHEMBL7065723 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2AHSD11B1POLBGAA | |
| SCHEMBL7062864 | 0.87 | FKBP1A (0.40) | ALDH1A1LMNATSHR | |
| SCHEMBL6232109 | 0.86 | TSHR (0.45) | ALDH1A1KMT2ATSHR | |
| SCHEMBL7062874 | 0.86 | TSHR (0.45) | ALDH1A1KMT2ATSHR | |
| SCHEMBL6229831 | 0.86 | TSHR (0.45) | ALDH1A1KMT2ATSHR | |
| SCHEMBL7066507 | 0.85 | FKBP1A (0.47) | TSHRNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7062139 | 0.85 | CHRNA1 (0.43) | ALDH1A1HSD11B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |