Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RBM39 | Q14498 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066486 | 0.86 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL915958 | 0.85 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7064614 | 0.83 | MAPT (0.44) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7064639 | 0.82 | MAPT (0.39) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7064638 | 0.82 | MAPT (0.39) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7064490 | 0.81 | ERN1 (0.43) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7066419 | 0.81 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7060993 | 0.81 | MAPT (0.42) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7062299 | 0.81 | GFER (0.48) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7065861 | 0.80 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313461-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | Melacure Therapeutics AB (SE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002011715-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | MELACURE THERAPEUTICS AB (SE) | 2002-02-14 | — | — | WO | disclosed |