Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719100 | 0.91 | ALDH1A1 (0.64) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8336482 | 0.79 | SMN1; SMN2 (0.58) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8337364 | 0.79 | SMN1; SMN2 (0.58) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL9721896 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL9870442 | 0.78 | KDM4E (0.71) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6715528 | 0.78 | HSD17B10 (0.53) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL6720054 | 0.77 | RAB9A (0.55) | MEN1KMT2APOLBMAPTHTT | |
| SCHEMBL13875344 | 0.76 | KMT2A (0.77) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6719158 | 0.76 | ULK1 (0.61) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6718828 | 0.76 | ALDH1A1 (0.61) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |