Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824484 | 0.94 | MAPK1 (0.54) | DRD2MAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1531299 | 0.83 | TDP1 (0.57) | MAPK1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6781971 | 0.81 | MAPK1 (0.52) | MAPK1MAPTALDH1A1SMN1; SMN2LMNA | |
| Potassium Ion SCHEMBL6716540 | 0.80 | MAPK1 (0.49) | MAPK1MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6714799 | 0.80 | MAPK1 (0.51) | DRD2MAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25607591 | 0.78 | LMNA (0.63) | DRD2MAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4192847 | 0.77 | MAPK1 (0.47) | MAPK1ALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL6785307 | 0.77 | HTR2C (0.54) | MAPK1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6824482 | 0.76 | MAPK1 (0.47) | MAPK1MAPTALDH1A1SMN1; SMN2LMNA | |
| Bicarbonate SCHEMBL6919502 | 0.76 | MAPK1 (0.47) | MAPK1MAPTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004010943-A2 | SUBSTITUTED BENZANILIDES AS MODULATORS OF THE CCR5 RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |