Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 3/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064746 | 0.93 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL31468453 | 0.85 | HTT (0.35) | KCNH2MEN1KMT2A | |
| SCHEMBL31468579 | 0.80 | SIGMAR1 (0.37) | KCNH2ALDH1A1TSHR | |
| SCHEMBL30872686 | 0.80 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL31468636 | 0.79 | HRH1 (0.34) | KCNH2ALDH1A1TSHRMEN1LMNA | |
| SCHEMBL27258709 | 0.78 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL31468521 | 0.77 | HTT (0.35) | KCNH2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27258912 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| Hexane SCHEMBL10533800 | 0.76 | ALDH1A1 (0.46) | KCNH2ALDH1A1CNR1THRATHRB | |
| SCHEMBL8192504 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859277-A | Silicon-containing solid support linker | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-01-12 | — | — | US | disclosed |