Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA4 | P22748 | 4/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673838 | 0.81 | SIGMAR1 (0.54) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL27428109 | 0.81 | SIGMAR1 (0.54) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL27564326 | 0.81 | SIGMAR1 (0.54) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL1090152 | 0.81 | SIGMAR1 (0.54) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL1090149 | 0.81 | SIGMAR1 (0.54) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL1763575 | 0.81 | SIGMAR1 (0.54) | SIGMAR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL1763150 | 0.80 | SIGMAR1 (0.53) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL8595774 | 0.80 | SIGMAR1 (0.53) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL11590269 | 0.80 | SIGMAR1 (0.53) | SIGMAR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL1763147 | 0.80 | SIGMAR1 (0.53) | SIGMAR1CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069266-A1 | Aids therapy | VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069266-A1 | Aids therapy | ENTPD5, CCR5, ITPA | SIGMAR1 1357/4885CA1 4721/4885CA2 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.