Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176422 | 0.87 | KDM4E (0.49) | SIGMAR1L3MBTL1RIPK1CHRNB2CHRNB4 | |
| SCHEMBL8129975 | 0.87 | SIGMAR1 (0.55) | SIGMAR1L3MBTL1RIPK1TSHRRECQL | |
| SCHEMBL20528485 | 0.86 | DPP4 (0.46) | SIGMAR1RIPK1DPP4DPP7HTR2C | |
| SCHEMBL21801033 | 0.86 | DPP4 (0.46) | SIGMAR1RIPK1DPP4DPP7HTR2C | |
| SCHEMBL2935422 | 0.86 | DPP4 (0.46) | SIGMAR1RIPK1DPP4DPP7HTR2C | |
| SCHEMBL7749807 | 0.86 | RIPK1 (0.46) | SIGMAR1RIPK1DPP4DPP7HTR2C | |
| Hydrochloric Acid SCHEMBL9258072 | 0.84 | DPP4 (0.46) | SIGMAR1RIPK1DPP4DPP7HTR2C | |
| SCHEMBL16150884 | 0.84 | SIGMAR1 (0.43) | SIGMAR1L3MBTL1CA1CA2CA4 | |
| SCHEMBL2386164 | 0.83 | DPP4 (0.47) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL8496002 | 0.83 | DPP4 (0.45) | SIGMAR1RIPK1DPP4DPP7HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875512-A2 | New naphthylpiperazine derivatives with antipsychotic activity | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1998-11-04 | — | — | EP | disclosed |