Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.46 |
| ▸ | HMGCR | P04035 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 8/20 | 0.40 |
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066330 | 0.81 | TNFRSF1A (0.42) | GABBR2GABBR1HMGCRMAOAMAOB | |
| SCHEMBL9218296 | 0.74 | GABBR2 (0.50) | GABBR2GABBR1HMGCREGFRCYP1A2 | |
| SCHEMBL5667712 | 0.74 | MAPT (0.35) | GABBR2GABBR1HMGCRCYP1A2 | |
| SCHEMBL10754138 | 0.71 | GABBR2 (0.68) | GABBR2GABBR1MAOAMAOBEGFR | |
| SCHEMBL10897581 | 0.71 | GABBR2 (0.68) | GABBR2GABBR1MAOAMAOBEGFR | |
| SCHEMBL6916852 | 0.70 | GABBR2 (0.55) | GABBR2GABBR1HMGCRMAOAMAOB | |
| SCHEMBL5712559 | 0.69 | GABBR2 (0.64) | GABBR2GABBR1CYP1A2CYP2C9TNFRSF1A | |
| SCHEMBL5712558 | 0.69 | GABBR2 (0.64) | GABBR2GABBR1CYP1A2CYP2C9TNFRSF1A | |
| SCHEMBL6917719 | 0.69 | GABBR2 (0.52) | GABBR2GABBR1HMGCRCYP1A2CYP2C9 | |
| SCHEMBL6910765 | 0.69 | GABBR2 (0.52) | GABBR2GABBR1HMGCREGFRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |