Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.50 |
| ▸ | HMGCR | P04035 | 3/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222763 | 0.80 | HMGCR (0.49) | GABBR2GABBR1HMGCRTNFRSF1APTGS1 | |
| SCHEMBL6910765 | 0.77 | GABBR2 (0.52) | GABBR2GABBR1HMGCRTNFRSF1APTGS1 | |
| SCHEMBL6917719 | 0.77 | GABBR2 (0.52) | GABBR2GABBR1HMGCRTNFRSF1APTGS1 | |
| SCHEMBL5663900 | 0.75 | RXRA (0.38) | TNFRSF1APTGS2ALOX5 | |
| SCHEMBL7063110 | 0.74 | GABBR2 (0.56) | GABBR2GABBR1HMGCRTNFRSF1APTGS1 | |
| SCHEMBL7065200 | 0.74 | GABBR2 (0.46) | GABBR2GABBR1HMGCRTNFRSF1APTGS1 | |
| SCHEMBL6916852 | 0.74 | GABBR2 (0.55) | GABBR2GABBR1HMGCRTNFRSF1APTGS1 | |
| Butane SCHEMBL9222761 | 0.73 | GABBR2 (0.48) | GABBR2GABBR1HMGCRTNFRSF1APTGS1 | |
| SCHEMBL9222066 | 0.73 | GABBR2 (0.54) | GABBR2GABBR1HMGCRPTGS1PTGS2 | |
| SCHEMBL9224042 | 0.72 | GABBR2 (0.47) | GABBR2GABBR1HMGCRTNFRSF1APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | claimed |