Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 4/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666846 | 0.83 | TNFRSF1A (0.32) | TNFRSF1AKDM4E | |
| SCHEMBL5667712 | 0.82 | MAPT (0.35) | KDM4EKMT2AMEN1GABBR2GABBR1 | |
| SCHEMBL7065200 | 0.81 | GABBR2 (0.46) | TNFRSF1AGABBR2GABBR1MAOAMAOB | |
| SCHEMBL7065034 | 0.72 | TNFRSF1A (0.50) | TNFRSF1AKDM4EKMT2AMEN1GABBR2 | |
| SCHEMBL6916935 | 0.72 | TNFRSF1A (0.50) | TNFRSF1AKDM4EKMT2AMEN1GABBR2 | |
| SCHEMBL7442575 | 0.70 | TNFRSF1A (0.56) | TNFRSF1AKDM4EKMT2AMEN1GABBR2 | |
| SCHEMBL7442572 | 0.70 | TNFRSF1A (0.56) | TNFRSF1AKDM4EKMT2AMEN1GABBR2 | |
| SCHEMBL7060718 | 0.69 | TNFRSF1A (0.49) | TNFRSF1AKDM4EKMT2AMEN1GABBR2 | |
| SCHEMBL7060721 | 0.69 | TNFRSF1A (0.49) | TNFRSF1AKDM4EKMT2AMEN1GABBR2 | |
| SCHEMBL6909695 | 0.68 | TNFRSF1A (0.46) | TNFRSF1AKDM4EKMT2AMEN1GABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |