SCHEMBL70653

SCHEMBL70653

O=C(O)c1ccc(Br)c(C(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
TSHR P16473 2/20 0.48
TP53 P04637 1/20 0.48
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
POLB P06746 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
PTGS2 P35354 1/20 0.46
TTR P02766 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
HTT P42858 1/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2889000 0.89 TDP1 (0.55) KDM4ECA12CA1CA2POLB
SCHEMBL27958984 0.85 AKR1C3 (0.55) AKR1C3
SCHEMBL616328 0.85 AKR1C3 (0.44) KDM4ETSHRTP53CA12CA1
Terephthalic Acid SCHEMBL11743717 0.84 TSHR (0.57) TSHRTP53CA12CA1CA2
SCHEMBL617049 0.82 GSK3B (0.47) KDM4ETSHRTP53CA12CA1
SCHEMBL30162908 0.82 TTR (0.52) KDM4ETSHRTP53CA12CA1
SCHEMBL71015 0.82 TTR (0.52) KDM4ETSHRTP53CA12CA1
SCHEMBL588825 0.81 TTR (0.56) KDM4ETSHRTP53CA12CA1
SCHEMBL29810232 0.81 TTR (0.56) KDM4ETSHRTP53CA12CA1
SCHEMBL4914225 0.81 KDM4E (0.46) KDM4ETSHRCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630763-B2 Composite material and preparation method thereof and quantum dot light-emitting diode TCL TECHNOLOGY GROUP CORPORATION (CN) 2026-05-19 US claimed
CN-116693772-A Multifunctional agglomerated carboxylic acid water reducer and preparation method thereof 科之杰新材料集团(贵州)有限公司 2023-09-05 CN claimed
CN-113893707-B C (C) 1 -C 4 Mixed matrix membrane with preferential permeation of hydrocarbon, preparation method and application thereof 天津工业大学 2023-06-23 CN claimed
US-20220328786-A1 COMPOSITE MATERIAL AND PREPARATION METHOD THEREOF AND QUANTUM DOT LIGHT-EMITTING DIODE TCL TECHNOLOGY GROUP CORPORATION (CN) 2022-10-13 US claimed
CN-113893707-A C1-C4Mixed matrix membrane with preferential permeation of hydrocarbon, preparation method and application thereof 天津工业大学 2022-01-07 CN claimed
CN-108690200-B Metal organic structure and method for producing same 丰田自动车株式会社 2021-07-16 CN claimed
CN-109312107-B Polyester and polyolefin molding compounds having biologically active properties and molded bodies produced therefrom 纺织和塑料研究协会图林根研究院 2020-10-30 CN claimed
EP-3464445-B1 POLYESTER AND POLYOLEFIN MOULDING COMPOUNDS WITH BIOACTIVE PROPERTIES AND MOULDED BODIES PRODUCED THEREFROM THUERINGISCHES INST FUER TEXTIL UND KUNSTSTOFF FORSCHUNG E V (DE) 2020-08-05 EP claimed
US-10702851-B2 Metal-organic framework and method of manufacturing the same TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2020-07-07 US claimed
EP-3381924-B1 METAL-ORGANIC FRAMEWORK AND METHOD OF MANUFACTURING THE SAME TOYOTA MOTOR CO LTD (JP) 2019-10-16 EP claimed
US-5922104-A Separation membranes prepared from polyamide polymers having 2,2'-bis (trifluoromethyl) biphenyl units and a process of separating gaseous mixtures using them KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1999-07-13 US claimed
EP-0376234-B2 Semipermeable membranes based on specified tetrabromobisphenol type polyesters PRAXAIR TECHNOLOGY INC (US) 1999-01-20 EP claimed
EP-0444690-B1 Semipermeable membranes based on polyesters of tetrabromobisphenol A PRAXAIR TECHNOLOGY INC (US) 1995-11-15 EP claimed
EP-0376235-B1 Semipermeable membranes based on specified 4,4'-(1H-alkylidene)bis[2,3,6-trialkylphenol] type polyesters PRAXAIR TECHNOLOGY INC (US) 1994-02-16 EP claimed
US-5055114-A Gas separation UNION CARBIDE INDUSTRIAL GASES TECHNOLOGY CORPORATION (US) 1991-10-08 US claimed
EP-0444690-A2 Semipermeable membranes based on polyesters of tetrabromobisphenol A PRAXAIR TECHNOLOGY, INC. (US) 1991-09-04 EP claimed
US-4994095-A Gas separation UNION CARBIDE INDUSTRIAL GASES TECHNOLOGY CORPORATION (US) 1991-02-19 US claimed
EP-0376235-A2 Semipermeable membranes based on specified 4,4'-(1H-alkylidene)bis[2,3,6-trialkylphenol] type polyesters PRAXAIR TECHNOLOGY, INC. (US) 1990-07-04 EP claimed
EP-0376234-A2 Semipermeable membranes based on specified tetrabromobisphenol type polyesters PRAXAIR TECHNOLOGY, INC. (US) 1990-07-04 EP claimed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10702851-B2 Metal-organic framework and method of manufacturing the same TRIM4, TRIM24, PICALM KDM4E 1786/4885TSHR 2816/4885TP53 1747/4885
US-12630763-B2 Composite material and preparation method thereof and quantum dot light-emitting diode CDH1, CDYL, MITF KDM4E 960/4885TSHR 2875/4885TP53 1200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.