Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067283 | 0.81 | MCL1 (0.42) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL7067278 | 0.81 | MCL1 (0.42) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL7065691 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL18298826 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL6488315 | 0.74 | MAPT (0.42) | ALDH1A1HPGDGAAKMT2AMAPT | |
| SCHEMBL7066317 | 0.71 | KMT2A (0.47) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL15985062 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL7129395 | 0.69 | MEN1 (0.39) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL11147862 | 0.69 | LMNA (0.42) | ALDH1A1LMNA | |
| SCHEMBL6488469 | 0.68 | SMN1; SMN2 (0.43) | ALDH1A1HPGDGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |