Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035387 | 0.79 | ADORA2A (0.42) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL18247 | 0.78 | PNP (0.59) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL1980958 | 0.77 | PNP (0.57) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL5667528 | 0.76 | ADORA2B (0.47) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL29015261 | 0.75 | ADORA2A (0.46) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL16494562 | 0.73 | PNP (0.35) | PNP | |
| SCHEMBL18250 | 0.73 | PNP (0.66) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL22631569 | 0.73 | PNP (0.49) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL1980960 | 0.72 | PNP (0.64) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL29026230 | 0.71 | PNP (0.36) | PNPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702683-B8 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER REC TECH LTD (GB) | 2004-09-08 | — | — | EP | disclosed |
| EP-0702683-A1 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |